Meet Our ESR – ESR 8 – Pauli TIKKA


We are very happy to introduce Pauli (ESR 8), who joined Franz Schaefer’s team in Heidelberg University Hospital in Germany:


“I am Pauli Tikka from Finland. I obtained my two Master of Science degrees (in the Energy Engineering and Biotechnology) from one of the leading universities in Finland; Aalto University and University of Turku. The latest one I completed during 2011-2014. My master’s thesis was entitled “the effect of miRNAs to the regulation of triple negative breast cancer cell”, where I mostly worked on an in silico model and bioinformatics approaches. The research work of that thesis was conducted at the Hans Knöll Institute under Professor Dr. Rainer König from the University of Jena. After my second Master of Science degree, I enhanced my university work skills at the University of Turku as a complementary student. Earlier, I have also worked as a design engineer in two companies and as a research scientist in the Aalto University during my first Master of Science degree. The subject of my earlier thesis was “gas evolution at the lead anodes”, and was done in the laboratory of physical chemistry for a project of Outotec Inc.
In the autumn of 2015, I took the next step in my scientific career path by applying and being later selected in the RENALTRACT research project. I started my research work at the Heidelberg University in January 2016 under the professors Dr. Franz Schaefer and Dr. Anna Marciniak-Czochra. My doctoral research will be mainly focused on the development of a set of mathematical models reproducing the molecular and cellular events that lead to kidney development. For this purpose, I will rigorously review the literature of nephrogenesis’ molecular networks and genetics, collaborate with Renaltract partner laboratories, and formulate sets of mathematical equations under the co-supervision of Prof. Dr. Anna Marciniak-Czochra. Furthermore, I will perform gene network and molecular pathway analyses, and cross-species approaches in order to understand the complex genetics of congenital malformations of the kidneys and urinary tract (CAKUT) in humans. These two branches of my studies will converge in an integrative bioinformatic model of normal and aberrant kidney development that shall allow the use of complex genetic information to predict human renal malformation phenotypes”.